Mood: The mood of the video appears to be light-hearted and playful, with a theme of friendship and its effects. The use of bright colors and casual clothing adds to the relaxed and informal atmosphere. The title 'Dosti Ke Side Effects' suggests that the video may explore the humorous side of friendships.

Environment: The setting appears to be an urban or semi-urban area, with a brick wall and a building in the background. The blue sky with clouds adds a sense of serenity to the scene. The overall setting seems to be casual and relaxed, possibly a college or university campus.